Kyle Fuller's half-court heave bounced off the back of the iron and Vanderbilt fell 67-64 at Missouri Wednesday night.
The undermanned Commodores hung with the Tigers all night long and even led 21-20 at the half.
James Siakam's gave the Dores a 51-48 lead in the second half, but Mizzou responded with a 13-2 run to seize control of the game.
The Dores battled to the end though, Shelby Moats hit a 3-point field goal with 19 seconds to play to draw the Commodores within two points, but they could not get any closer.
Freshman Damian Jones turned in another solid performance for the Dores with 19 points and 7 rebounds. It was another tough night for senior Rod Odom who hit just three of 13 shots for 10 points.
Jordan Clarkson led Missouri with 21 points.
Vanderbilt falls to 14-11, 6-7 in the SEC.