Vanderbilt's losing streak in Knoxville hit 29 games with an81-53 loss Monday at Thompson-Boling Arena.
Meighan Simmons scored 22 points for the 8thranked Lady Vols. Christina Foggie also had 22 to lead Vanderbilt.
The Lady Vols pounded Vanderbilt on the glass 34-20 and shota scorching 58 percent for the game.
Tennessee clinched its 38th consecutive 20-winseason with the victory.