A 23-year-old is in critical condition after his Ford Escape hit a guardrail and flipped several times.
The accident happened just after Midnight Friday near Briley Parkway and Opry Mills Drive.
The driver, whose name was not released, was transported to Vanderbilt University Medical Center with life-threatening injuries.
Metro police told Nashville's News 2 there was evidence of alcohol at the scene.
Authorities said the contributing factor in the crash is failure to maintain a lane of travel.